What is the difference between Mounjaro and Wegovy?

Mounjaro (Tirzepatide) is a dual GIP/GLP-1 agonist, while Wegovy (Semaglutide) is a GLP-1–only medication. Clinical trials show higher average weight loss with Tirzepatide, but individual results vary and depend on medical suitability.

Is Mounjaro more effective than Wegovy for weight loss?

Trials suggest Tirzepatide can reach up to ~22.5% weight loss vs. ~15% with Semaglutide. Effectiveness depends on dosing, adherence, and your health history—only a licensed provider can advise what is best for you.

How much does Mounjaro cost without insurance?

Brand Mounjaro can be expensive without coverage. Telehealth clinics may offer compounded Tirzepatide with memberships starting around $199/month. Prices vary by dosage, location, and clinic policies.

How much does Wegovy cost without insurance?

Brand Wegovy is often costly at retail. Telehealth options for Semaglutide, including compounded versions, can start near $99/month depending on dose and clinic membership models.

Can I get Mounjaro or Wegovy online legally?

Yes—through licensed telehealth providers that perform medical evaluations and issue prescriptions when appropriate. A valid prescription is required for all GLP-1 medications.

What is compounded Tirzepatide or Semaglutide?

Compounded medications are prepared by licensed compounding pharmacies using the same active ingredient. Availability and legality depend on regulations and sourcing; discuss risks and benefits with your provider.

Which GLP-1 medication should I choose?

Consider your medical history, goals, budget, and provider guidance. Take our educational quiz for a starting point, then consult a licensed healthcare professional for a personalized decision.

Are online GLP-1 prescriptions legitimate?

They can be, when issued by licensed clinicians via reputable telehealth platforms. Verify the provider’s credentials, pharmacy partners, and safety practices before proceeding.

Updated November 2025 • 8+ Clinics Compared • Educational Resource

Mounjaro vs Wegovy: Which Is Right for You?

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Head-to-Head Comparison

Mounjaro vs Wegovy at a Glance

Key differences between Tirzepatide and Semaglutide. Use this as a starting point—talk to your provider for medical advice.

MOUNJARO

Tirzepatide

WEGOVY

Semaglutide

Generic

Tirzepatide

Semaglutide

Mechanism

Dual GIP/GLP-1

GLP-1 only

Avg Loss

Up to 22.5%

Up to 15%

From

$199/month

$99/month

Frequency

Weekly

FDA Approved

✓

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Choose Your Medication

Two Powerful Options for Weight Loss

Both are FDA-approved GLP-1 medications prescribed by licensed healthcare providers.

Most Effective

Mounjaro

Mounjaro® • Zepbound® • Compounded

Clinical results

Up to 22.5% weight loss in clinical trials

From $199/month

Dual GIP/GLP-1 action
Once-weekly injection
FDA approved for weight loss
Available via telehealth

Compare Mounjaro Prices

Requires prescription from licensed provider.

Wegovy

Wegovy® • Ozempic® • Compounded

Clinical results

Up to 15% weight loss in clinical trials

From $99/month

Proven GLP-1 medication
Once-weekly injection
FDA approved for weight loss
More affordable options

Compare Wegovy Prices

Requires prescription from licensed provider.

Prices shown are from third-party telehealth providers. We do not sell medications directly.

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22.5% average weight loss with Tirzepatide (SURMOUNT trials)

15% average weight loss with Semaglutide (STEP trials)

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Please Note

This website provides educational information and price comparisons only. We are not medical providers and do not prescribe medications. The clinics listed are independent third-party telehealth services. A licensed healthcare provider will determine if GLP-1 medications are appropriate for you.

Common Questions

Frequently Asked Questions

Everything you need to know about Mounjaro, Wegovy, and GLP-1 medications.

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